Description

6-Chloro-1,7-naphthyridin-2(1H)-one is a high-purity, heterocyclic organic compound serving as a critical advanced intermediate in modern chemical synthesis. Its unique fused-ring structure makes it a valuable building block for constructing complex molecules with targeted biological and material properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology: Employed as a molecular probe or scaffold in the study of biological pathways and protein interactions.
• Academic & Industrial R&D: Utilized in synthetic organic chemistry laboratories for methodological studies and the construction of complex heterocyclic libraries.

Basic Information

Product Name	6-Chloro-1,7-naphthyridin-2(1H)-one
CAS No.	291514-02-8
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	6-Chloro-1,7-naphthyridin-2(1H)-one; 6-Chloro-1,7-naphthyridin-2-ol; 2-Chloro-1,7-naphthyridin-6(5H)-one; 6-Chloro-2-hydroxy-1,7-naphthyridine; 291514-02-8; 6-Chloro-1H-1,7-naphthyridin-2-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,7-naphthyridin-2(1H)-one is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We support cGMP compliance for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.