Description

1,1Bis((2S,5S)-2,5-Diethylphospholano)Ferrocene(Cyclooctadiene)Rhodium(I) Tetrafluoroborate is a highly specialized, chiral organometallic catalyst complex. This compound is valued for its exceptional stereoselectivity and catalytic efficiency in asymmetric hydrogenation and other transition metal-catalyzed reactions. It is a critical reagent for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high enantiomeric purity in their synthetic pathways.

Application

• Asymmetric Hydrogenation Catalyst: A premier catalyst for the enantioselective reduction of prochiral olefins, enamines, and ketones to produce chiral intermediates.
• Pharmaceutical Intermediate Synthesis: Enables the production of single-enantiomer active pharmaceutical ingredients (APIs) for drugs targeting CNS disorders, cardiovascular diseases, and infectious diseases.
• Agrochemical Manufacturing: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators where biological activity is enantiomer-specific.
• Fine Chemical and Fragrance Production: Facilitates the creation of complex, high-value chiral molecules for flavors, fragrances, and advanced materials.
• Academic and Industrial R&D: Serves as a key tool in methodological development for new catalytic asymmetric transformations in both university and corporate research laboratories.
• Process Chemistry Optimization: Employed in scaling up enantioselective reactions from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	1,1Bis((2S,5S)-2,5-Diethylphospholano)Ferrocene(Cyclooctadiene)Rhodium(I) Tetrafluoroborate
CAS No.	290347-88-5
Molecular Formula	C30H46BF4FeP2Rh
Molecular Weight	690.21 g/mol
Synonyms	(S,S)-1,1'-Bis(2,5-diethylphospholano)ferrocene(cyclooctadiene)rhodium(I) tetrafluoroborate; (S,S)-Et-FerroTANE Rh(I) BF4; Rh-(S,S)-Et-FerroTANE COD tetrafluoroborate; (S,S)-Et-DuPHOS-Rh(COD)BF4 analogue; Chiral ferrocenylphosphine-rhodium complex; [Rh((S,S)-Et-FerroTANE)(COD)]BF4; Asymmetric hydrogenation catalyst precursor; (2S,5S)-1,1'-Bis(2,5-diethylphospholanyl)ferrocene-rhodium(I)-1,5-cyclooctadiene tetrafluoroborate
EINECS	Contact for details

Quality Control

Our catalyst is manufactured under strict quality control protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot is characterized by NMR, HPLC, and elemental analysis to confirm identity, chiral purity, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess (ee) of the ligand, and impurity profile is provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (argon or nitrogen). This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light will degrade catalytic activity. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline solid or powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (ee of Ligand)	≥ 98.0%
Rhodium Content (ICP-MS)	14.5 - 15.5 %
Solubility	Soluble in dichloromethane, THF; sparingly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.