Description

4-(5-Chlorothiophen-2-Yl)Benzoic Acid is a high-purity organic building block featuring a benzoic acid moiety linked to a chlorinated thiophene ring. This compound matters as a versatile and critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs), enabling precise molecular design. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the thiophene scaffold.
• Material Science Research: Serves as a precursor for organic electronic materials, such as semiconductors and conductive polymers.
• Ligand and Catalyst Development: The carboxylic acid group allows for functionalization into complex chelating agents for metal catalysis.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for bespoke chemical synthesis projects.
• Academic & Industrial R&D: A valuable tool for exploratory chemistry in medicinal and synthetic organic chemistry laboratories.

Basic Information

Product Name	4-(5-Chlorothiophen-2-Yl)Benzoic Acid
CAS No.	290326-23-7
Molecular Formula	C11H7ClO2S
Molecular Weight	238.69 g/mol
Synonyms	[4-(5-Chlorothiophen-2-yl)phenyl]methanoic Acid; 4-(5-Chloro-2-thienyl)benzoic Acid; 5-Chloro-2-(4-carboxyphenyl)thiophene; 2-(4-Carboxyphenyl)-5-chlorothiophene; Benzoic acid, 4-(5-chloro-2-thienyl)-; 290326-23-7; 4-(5-Chloro-thiophen-2-yl)-benzoic acid
EINECS	Contact for details

Quality Control

Our 4-(5-Chlorothiophen-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.