Description

7-Chloro-2-(Chloromethyl)-6-Methylquinazolin-4(3H)-One is a high-purity, synthetically versatile quinazolinone derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional chlorinated structure makes it an indispensable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique thermal or optical properties.
• Dye & Pigment Industry: Functions as an intermediate in the synthesis of advanced colorants and fluorescent markers.

Basic Information

Product Name	7-Chloro-2-(Chloromethyl)-6-Methylquinazolin-4(3H)-One
CAS No.	289686-83-5
Molecular Formula	C10H8Cl2N2O
Molecular Weight	243.09 g/mol
Synonyms	7-Chloro-2-(chloromethyl)-6-methyl-3,4-dihydroquinazolin-4-one; 7-Chloro-2-(chloromethyl)-6-methyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 7-chloro-2-(chloromethyl)-6-methyl-; 2-(Chloromethyl)-7-chloro-6-methylquinazolin-4(3H)-one; 6-Methyl-7-chloro-2-chloromethyl-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-(Chloromethyl)-6-Methylquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.