Description

1,8-Naphthyridine-2-Carboxamide,n-[3-(Trifluoromethyl)Phenyl]-(9Ci) is a specialized heterocyclic organic compound featuring a naphthyridine core functionalized with a carboxamide group and a trifluoromethylphenyl substituent. This molecular architecture makes it a valuable high-purity building block and key intermediate in advanced chemical synthesis, particularly for applications demanding precise structural control. It is primarily utilized by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and functional materials. The compound is supplied with CAS No. 289677-03-8.

Application

This compound serves as a critical intermediate in several high-value research and development sectors:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the biological activity of the naphthyridine scaffold.
• Chemical Biology & Medicinal Chemistry: Employed as a molecular probe or building block for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Research: Investigated as a component for organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, conjugated structure and coordination sites.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	1,8-Naphthyridine-2-Carboxamide,n-[3-(Trifluoromethyl)Phenyl]-(9Ci)
CAS No.	289677-03-8
Molecular Formula	C₁₆H₁₀F₃N₃O
Molecular Weight	317.27 g/mol
Synonyms	N-[3-(Trifluoromethyl)phenyl]-1,8-naphthyridine-2-carboxamide; 1,8-Naphthyridine-2-carboxamide, N-[3-(trifluoromethyl)phenyl]-; 289677-03-8; 2-Naphthyridinecarboxamide, N-[3-(trifluoromethyl)phenyl]-1,8-; N-(3-Trifluoromethylphenyl)-1,8-naphthyridine-2-carboxamide
EINECS	Contact for details

Quality Control

Our high-purity chemical intermediates are produced and tested under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.