Description

2-Chloro-5-Iodophenol is a halogenated phenol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the construction of complex molecular architectures, particularly in pharmaceutical and agrochemical research. Its unique substitution pattern makes it a valuable precursor for coupling reactions and the development of active pharmaceutical ingredients (APIs), liquid crystal materials, and specialized ligands.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for monomers and polymers, and in the development of organic electronic materials and liquid crystals.
• Chemical Research: Employed as a standard or reagent in Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Dye & Pigment Industry: Acts as an intermediate for the synthesis of specialized halogenated dyes and colorants.
• Ligand Synthesis: Useful for creating complexing agents and chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	2-Chloro-5-Iodophenol
CAS No.	289039-26-5
Molecular Formula	C6H4ClIO
Molecular Weight	254.45 g/mol
Synonyms	5-Iodo-2-chlorophenol; 2-Chloro-5-iodo-1-hydroxybenzene; Phenol, 2-chloro-5-iodo-; 2-Chloro-5-iodophenol; 1-Hydroxy-2-chloro-5-iodobenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Iodophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming identity, assay, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.