Description

2-Bromo-4-Fluorocinnamic Acid is a halogenated cinnamic acid derivative that serves as a versatile and high-value synthetic building block. Its molecular structure, featuring both bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers engaged in the synthesis of novel active ingredients, particularly in medicinal chemistry for creating potential drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small molecule drugs, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, where the halogen atoms can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers with unique optical or electronic properties.
• Liquid Crystal & OLED Development: The cinnamic acid core and halogenated aromatic ring are valuable for synthesizing organic semiconductors and liquid crystal materials for displays.
• Chemical Biology Probes: Utilized in creating tagged molecules or photoaffinity labels for studying biological pathways and protein interactions.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other transformations to introduce functionalized aromatic systems into target molecules.

Basic Information

Product Name	2-Bromo-4-Fluorocinnamic Acid
CAS No.	289038-17-1
Molecular Formula	C9H6BrFO2
Molecular Weight	245.05 g/mol
Synonyms	(E)-3-(2-Bromo-4-fluorophenyl)acrylic acid; 2-Bromo-4-fluorocinnamic acid; trans-2-Bromo-4-fluorocinnamic acid; (2E)-3-(2-Bromo-4-fluorophenyl)-2-propenoic acid; 3-(2-Bromo-4-fluorophenyl)prop-2-enoic acid; β-(2-Bromo-4-fluorophenyl)acrylic acid; 2-Bromo-4-fluoro-trans-cinnamic acid
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorocinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.