Description

4-Fluoro-2-(1H-Pyrazol-3-Yl)Phenol CAS NO 288401-64-9 is a high-value fluorinated phenolic compound containing a pyrazole heterocycle, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, combining fluorine and a nitrogen-containing heterocycle, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and anti-inflammatory agent discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom and pyrazole moiety contribute to efficacy and environmental profile.
• Ligand for Catalysis: Serves as a precursor for creating specialized ligands used in transition metal catalysis for fine chemical manufacturing.
• Material Science Research: Investigated as a monomer or additive for developing novel polymers with specific thermal or optical properties.
• Chemical Biology Probes: Utilized in academic and industrial research to create molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	4-Fluoro-2-(1H-Pyrazol-3-Yl)Phenol
CAS No.	288401-64-9
Molecular Formula	C9H7FN2O
Molecular Weight	178.16 g/mol
Synonyms	4-Fluoro-2-(1H-pyrazol-3-yl)phenol; 2-(1H-Pyrazol-3-yl)-4-fluorophenol; 4-Fluoro-2-(1H-pyrazol-5-yl)phenol; 288401-64-9; 4-Fluoro-2-(3-pyrazolyl)phenol; Phenol, 4-fluoro-2-(1H-pyrazol-3-yl)-; 3-(5-Fluoro-2-hydroxyphenyl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our production of 4-Fluoro-2-(1H-Pyrazol-3-Yl)Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.