Description

(E)-3-(1H-Indol-7-Yl)Acrylic Acid CAS NO 288371-43-7 is a high-purity, synthetic organic compound featuring an indole core conjugated to an acrylic acid moiety via an ethylene bridge. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a crucial building block for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery.
• Bioconjugation & Probe Development: The acrylic acid group enables coupling reactions for creating fluorescent probes, affinity labels, or protein conjugates for biochemical studies.
• Organic Synthesis: Used in various organic transformations, including Michael additions, cyclizations, and polymerizations to create novel materials.
• Agrochemical Research: Potential intermediate in the development of new plant growth regulators or pesticides with specific biological activity.

Basic Information

Product Name	(E)-3-(1H-Indol-7-Yl)Acrylic Acid
CAS No.	288371-43-7
Molecular Formula	C11H9NO2
Molecular Weight	187.20 g/mol
Synonyms	(2E)-3-(1H-Indol-7-yl)prop-2-enoic acid; 3-(1H-Indol-7-yl)acrylic acid; 7-Indolylacrylic acid; trans-3-(1H-Indol-7-yl)acrylic acid; (E)-3-(1H-Indol-7-yl)-2-propenoic acid; 2-Propenoic acid, 3-(1H-indol-7-yl)-, (2E)-; 288371-43-7; 7-(2-Carboxyvinyl)indole
EINECS	Contact for details

Quality Control

Our (E)-3-(1H-Indol-7-Yl)Acrylic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research and pharmaceutical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.