Description

S-n-(-)-p-Tolylsulfinyltryptamine is a high-purity chiral sulfoxide derivative of tryptamine, serving as a sophisticated synthetic intermediate in advanced organic chemistry. Its primary value lies in its role as a key building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel therapeutics, including central nervous system (CNS) agents and other bioactive compounds requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the research and synthesis of novel drug candidates, particularly in neuroscience and neuropharmacology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new therapeutic agents.
• Asymmetric Synthesis: Employed as a chiral auxiliary or reagent in stereoselective synthesis to create enantiomerically pure compounds.
• Biochemical Tool Compound: Utilized in academic and industrial research to study biological pathways and receptor interactions.
• Process Chemistry Development: Serves as a standard or reference material in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the life sciences industry.

Basic Information

Product Name	S-n-(-)-p-Tolylsulfinyltryptamine
CAS No.	288159-11-5
Molecular Formula	C19H20N2OS
Molecular Weight	324.44 g/mol
Synonyms	(S)-(-)-p-Tolylsulfinyltryptamine; (S)-(-)-4-Methylphenylsulfinyltryptamine; (S)-N-[2-(1H-Indol-3-yl)ethyl]-4-methylbenzenesulfinamide; S-(-)-p-Tolylsulfinyltryptamine; S-n-(-)-p-Tolylsulfinyltryptamine; Tryptamine, N-[(4-methylphenyl)sulfinyl]-, (S)-; S-(-)-4-Methylbenzenesulfinyltryptamine
EINECS	Contact for details

Quality Control

Our S-n-(-)-p-Tolylsulfinyltryptamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.