Description

R-(+)-n-p-Tolylsulfinyltryptamine is a chiral sulfoxide derivative of tryptamine, characterized by its specific (R)-(+)-enantiomeric configuration and a p-tolylsulfinyl substituent. This compound is a valuable high-purity synthetic intermediate and a key building block in advanced organic synthesis, particularly for the development of novel pharmaceuticals and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of potential drug candidates targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis.
• Asymmetric Synthesis: Serves as a chiral auxiliary or substrate in stereoselective chemical transformations due to its sulfinyl group.
• Biochemical Research: Potential use in studying serotonin receptor analogs and related biochemical pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	R-(+)-n-p-Tolylsulfinyltryptamine
CAS No.	288158-92-9
Molecular Formula	C19H20N2OS
Molecular Weight	324.44 g/mol
Synonyms	(R)-(+)-1-(p-Tolylsulfinyl)-1H-indole-3-ethanamine; (R)-(+)-1-[(4-Methylphenyl)sulfinyl]-1H-indole-3-ethanamine; (R)-(+)-1-(4-Methylbenzenesulfinyl)indole-3-ethylamine; (R)-(+)-n-p-Tolylsulfinyltryptamine; R-(+)-p-Tolylsulfinyltryptamine; (R)-(+)-Tolylsulfinyltryptamine; R-TST; (R)-Tolylsulfinyltryptamine
EINECS	Contact for details

Quality Control

Our R-(+)-n-p-Tolylsulfinyltryptamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles for the production of advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (R-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.