Description

4-Amino-5,7-Difluoro-2-Methyl-Quinoline is a high-purity, fluorinated quinoline derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmaceutical intermediates and agrochemicals, where its unique substitution pattern enables precise molecular design. It is primarily sought by research institutions and industrial manufacturers in the life sciences sector for creating active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in developing new-generation herbicides and pesticides, leveraging the fluorine atoms for improved bioavailability and environmental stability.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and organic electronic materials.
• Fluorescent Probe Synthesis: The quinoline core is utilized in constructing molecular probes and sensors for biochemical imaging and diagnostics.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and other catalytic processes to introduce the difluoroquinoline scaffold into more complex molecules.

Basic Information

Product Name	4-Amino-5,7-Difluoro-2-Methyl-Quinoline
CAS No.	288151-43-9
Molecular Formula	C₁₀H₈F₂N₂
Molecular Weight	194.18 g/mol
Synonyms	2-Methyl-4-amino-5,7-difluoroquinoline; 5,7-Difluoro-2-methylquinolin-4-amine; 4-Amino-5,7-difluoro-2-methylquinoline; 2-Methyl-5,7-difluoroquinolin-4-amine; 288151-43-9; Quinoline, 4-amino-5,7-difluoro-2-methyl-; 4-Amino-5,7-difluoro-2-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-5,7-Difluoro-2-Methyl-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.