Description

4-Chloro-5,7-Difluoro-2-Methyl-Quinoline is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated quinoline structure, which provides a versatile scaffold for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, particularly those targeting infectious diseases, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient quinoline core.
• Ligand and Catalyst Development: Employed as a starting material for creating specialized ligands used in transition metal catalysis for complex bond-forming reactions.
• Fluorescent Probe Synthesis: The difluoro-substituted quinoline structure is advantageous for creating fluorescent dyes and molecular probes for bioimaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies engaged in custom synthesis projects for clients in life sciences and specialty chemicals.

Basic Information

Product Name	4-Chloro-5,7-Difluoro-2-Methyl-Quinoline
CAS No.	288151-41-7
Molecular Formula	C₁₀H₆ClF₂N
Molecular Weight	213.61 g/mol
Synonyms	2-Methyl-4-chloro-5,7-difluoroquinoline; 5,7-Difluoro-4-chloro-2-methylquinoline; 4-Chloro-5,7-difluoro-2-methylquinoline; Quinoline, 4-chloro-5,7-difluoro-2-methyl-; 288151-41-7; 4-Chloro-5,7-difluoro-2-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,7-Difluoro-2-Methyl-Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.