Description

5,7-Difluoro-2-Methyl-Quinolin-4-Ol is a fluorinated quinoline derivative, a versatile heterocyclic building block prized for its unique electronic and steric properties. This compound is critical for advanced research and development in medicinal chemistry and materials science, where its structure enables the fine-tuning of molecular interactions. It is primarily sought by pharmaceutical researchers for drug discovery programs and by agrochemical developers for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents, leveraging the fluorine atoms to enhance bioavailability and environmental stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or host molecules in the fabrication of high-efficiency display and lighting technologies.
• Fluorescent Probe Synthesis: Utilized to construct sophisticated molecular probes and sensors for bioimaging and diagnostic applications due to the quinoline fluorophore core.
• Ligand for Catalysis: Employed in the design of novel ligands for transition metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Investigated as a building block for advanced polymers and organic semiconductors with tailored electronic properties.

Basic Information

Product Name	5,7-Difluoro-2-Methyl-Quinolin-4-Ol
CAS No.	288151-40-6
Molecular Formula	C10H7F2NO
Molecular Weight	195.17 g/mol
Synonyms	4-Hydroxy-5,7-difluoro-2-methylquinoline; 5,7-Difluoro-2-methyl-4-quinolinol; 2-Methyl-5,7-difluoroquinolin-4-ol; 5,7-Difluoro-2-methyl-4-hydroxyquinoline; 4-Quinolinol, 5,7-difluoro-2-methyl-; 288151-40-6; 5,7-Difluoro-2-methyl-4(1H)-quinolinone (tautomer)
EINECS	Contact for details

Quality Control

Our 5,7-Difluoro-2-Methyl-Quinolin-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and scale-up with custom purity grades to meet specific project requirements from research to pilot plant scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (Higher grades available)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.