Description

4-Amino-8-Fluoro-2-Methylquinoline is a high-purity, functionalized quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and fluoro substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly in the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers, dyes, and organic electronic materials.
• Chemical Research & Development: Employed as a standard or reagent in methodological studies for fluorination and amination reactions in heterocyclic chemistry.
• Ligand Synthesis: Useful for constructing complex chelating ligands in coordination chemistry and catalysis.

Basic Information

Product Name	4-Amino-8-Fluoro-2-Methylquinoline
CAS No.	288151-34-8
Molecular Formula	C10H9FN2
Molecular Weight	176.19 g/mol
Synonyms	8-Fluoro-2-methylquinolin-4-amine; 2-Methyl-8-fluoroquinolin-4-amine; 4-Amino-8-fluoro-2-methylquinoline; 288151-34-8; Quinoline, 4-amino-8-fluoro-2-methyl-; 8-Fluoro-2-methyl-4-quinolinamine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-8-Fluoro-2-Methylquinoline is manufactured under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to minimize exposure to atmospheric moisture and light to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.