Description

4-Amino-6,8-Difluoro-2-Methylquinoline is a high-purity, multifunctional quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique difluoro-substituted quinoline scaffold, which is essential for constructing complex molecules with tailored biological and material properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in antimicrobial, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinoline core.
• Material Science Research: Serves as a precursor for developing organic semiconductors, fluorescent dyes, and photoactive materials due to its conjugated structure.
• Chemical Research & Development: Employed as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Preparation: Utilized to synthesize complex nitrogen-containing ligands for coordination chemistry and catalytic applications.

Basic Information

Product Name	4-Amino-6,8-Difluoro-2-Methylquinoline
CAS No.	288151-32-6
Molecular Formula	C10H8F2N2
Molecular Weight	194.18 g/mol
Synonyms	2-Methyl-4-amino-6,8-difluoroquinoline; 6,8-Difluoro-2-methylquinolin-4-amine; 4-Amino-6,8-difluoro-2-methylquinoline; 2-Methyl-6,8-difluoroquinolin-4-amine; 288151-32-6; Quinoline, 4-amino-6,8-difluoro-2-methyl-; 4-Amino-6,8-difluoro-2-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Amino-6,8-Difluoro-2-Methylquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.