Description

4-Chloro-6,8-Difluoro-2-Methyl-Quinoline is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated quinoline structure makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated quinoline core.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, dyes, and photoactive compounds.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Chemical Biology Probes: Acts as a scaffold for developing fluorescent tags and molecular probes for biological imaging and diagnostic applications.

Basic Information

Product Name	4-Chloro-6,8-Difluoro-2-Methyl-Quinoline
CAS No.	288151-31-5
Molecular Formula	C10H6ClF2N
Molecular Weight	213.61 g/mol
Synonyms	2-Methyl-4-chloro-6,8-difluoroquinoline; 6,8-Difluoro-4-chloro-2-methylquinoline; 4-Chloro-6,8-difluoro-2-methylquinoline; Quinoline, 4-chloro-6,8-difluoro-2-methyl-; 288151-31-5; 4-Chloro-6,8-difluoro-2-methyl-quinoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,8-Difluoro-2-Methyl-Quinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.