Description

4-Amino-5,8-Difluoro-2-Methyl-Quinoline is a high-purity, fluorinated quinoline derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological and material properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-infective research.
• Agrochemical Development: Used in creating advanced pesticides and herbicides, leveraging the fluorine atoms for enhanced bioactivity and stability.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor for electron-transport or host materials in display and lighting technologies.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorescent Probe & Dye Chemistry: Utilized in the development of specialized fluorophores for bio-imaging and sensor applications.
• Academic & Contract Research: Essential reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	4-Amino-5,8-Difluoro-2-Methyl-Quinoline
CAS No.	288151-30-4
Molecular Formula	C10H8F2N2
Molecular Weight	194.18 g/mol
Synonyms	2-Methyl-4-amino-5,8-difluoroquinoline; 5,8-Difluoro-4-amino-2-methylquinoline; 4-Amino-5,8-difluoro-2-methylquinoline; 288151-30-4; Quinoline, 4-amino-5,8-difluoro-2-methyl-; 2-Methyl-5,8-difluoroquinolin-4-amine
EINECS	Contact for details

Quality Control

Our 4-Amino-5,8-Difluoro-2-Methyl-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.