Description

5,8-Difluoro-2-Methyl-Quinolin-4-Ol is a high-value, multi-functional quinoline derivative distinguished by its unique fluorinated structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transport material or a core structure for emissive layer dopants in display and lighting technologies.
• Ligand in Catalysis: Serves as a chelating ligand for transition metals in catalytic systems designed for cross-coupling and other fine chemical reactions.
• Fluorescent Probe Development: Utilized in research to create sensitive molecular probes for bio-imaging and diagnostic assays due to its fluorophore backbone.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific optical or electronic properties.

Basic Information

Product Name	5,8-Difluoro-2-Methyl-Quinolin-4-Ol
CAS No.	288151-26-8
Molecular Formula	C₁₀H₇F₂NO
Molecular Weight	195.17 g/mol
Synonyms	4-Hydroxy-5,8-difluoro-2-methylquinoline; 5,8-Difluoro-2-methyl-4-quinolinol; 2-Methyl-5,8-difluoroquinolin-4-ol; 5,8-Difluoro-2-methyl-4-hydroxyquinoline; 4-Quinolinol, 5,8-difluoro-2-methyl-; 288151-26-8; SCHEMBL23842227
EINECS	Contact for details

Quality Control

Our 5,8-Difluoro-2-Methyl-Quinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.