Description

2,3-Dioxabicyclo[2.2.2]Oct-5-Ene,1-Methyl-4-(1-Methylethyl)-,(1S,4R)-(9Ci) is a high-purity, stereochemically defined bicyclic acetal compound, serving as a valuable chiral building block and synthetic intermediate. Its rigid, oxygenated structure makes it a critical precursor for the synthesis of complex natural products, pharmaceuticals, and specialty fine chemicals where precise stereochemistry is paramount. This compound is essential for research and development chemists in pharmaceutical, agrochemical, and advanced material sectors seeking to introduce specific chiral motifs and functional groups.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where biological activity is enantiomer-dependent.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts.
• Natural Product Synthesis: A crucial building block for the total synthesis of complex terpenoids and other oxygenated natural products.
• Material Science Research: Investigated for incorporation into chiral polymers or as a template for creating molecularly imprinted polymers (MIPs).
• Flavor & Fragrance Chemistry: Potential intermediate for creating stereochemically pure aroma chemicals and flavors.

Basic Information

Product Name	2,3-Dioxabicyclo[2.2.2]Oct-5-Ene,1-Methyl-4-(1-Methylethyl)-,(1S,4R)-(9Ci)
CAS No.	287968-09-6
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1S,4R)-1-Methyl-4-(1-methylethyl)-2,3-dioxabicyclo[2.2.2]oct-5-ene; (1S,4R)-1-Isopropyl-4-methyl-2,3-dioxabicyclo[2.2.2]oct-5-ene; (1S,4R)-p-Menthane-1,4-endoperoxide; Chiral Bicyclic Acetal; 2,3-Dioxabicyclo[2.2.2]oct-5-ene, 1-methyl-4-(1-methylethyl)-, (1S,4R)-; (-)-1-Methyl-4-isopropyl-2,3-dioxabicyclo[2.2.2]oct-5-ene; (1S,4R)-1-Methyl-4-isopropyl-2,3-dioxabicyclo[2.2.2]oct-5-ene
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dioxabicyclo[2.2.2]Oct-5-Ene,1-Methyl-4-(1-Methylethyl)-,(1S,4R)-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, GC, and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.