Description

2-[3-(2-Pyridin-3-Yl-Ethyl)-[1,2,4]Oxadiazol-5-Yl]-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug molecules, especially those with oxadiazole and pyrrolidine pharmacophores.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization studies for developing new active pharmaceutical ingredients (APIs).
• Process Chemistry & Scale-Up: Serves as a critical intermediate for process route development and pilot-scale production of target compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacology studies.

Basic Information

Product Name	2-[3-(2-Pyridin-3-Yl-Ethyl)-[1,2,4]Oxadiazol-5-Yl]-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	287963-69-3
Molecular Formula	C19H26N4O3
Molecular Weight	358.44 g/mol
Synonyms	tert-Butyl 2-[3-[2-(pyridin-3-yl)ethyl]-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2-[3-[2-(3-pyridyl)ethyl]-1,2,4-oxadiazol-5-yl]pyrrolidine; 2-(3-(2-(Pyridin-3-yl)ethyl)-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxylic acid tert-butyl ester; BOC-protected oxadiazole-pyrrolidine intermediate; 287963-69-3; Pyrrolidine-1-carboxylic acid, 2-[3-[2-(3-pyridinyl)ethyl]-1,2,4-oxadiazol-5-yl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-[3-(2-Pyridin-3-Yl-Ethyl)-[1,2,4]Oxadiazol-5-Yl]-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS, IR), to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to client specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.