Description

tert-Butyl Allyl(1,3-Dioxoisoindolin-2-Yl)Carbamate is a specialized organic building block featuring a phthalimide-protected amine and an allyl carbamate group. This compound matters as a versatile intermediate for the synthesis of complex molecules, offering orthogonal protection strategies and enabling selective chemical transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other small molecule drugs.
• Peptide Mimetics & PROTACs: Used in the construction of peptide backbones and as a linker component in Proteolysis Targeting Chimeras (PROTACs) due to its cleavable protecting groups.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of novel polymers with specific functional properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	tert-Butyl Allyl(1,3-Dioxoisoindolin-2-Yl)Carbamate
CAS No.	287729-03-7
Molecular Formula	C₁₆H₁₈N₂O₄
Molecular Weight	302.33 g/mol
Synonyms	2-[(Allyloxy)carbonyl]-1,3-dioxoisoindoline-5-carboxylic acid tert-butyl ester; tert-Butyl N-allyl-N-(1,3-dioxoisoindolin-2-yl)carbamate; Allyl tert-butyl (1,3-dioxoisoindolin-2-yl)carbamate; 2-(N-Allyl-N-tert-butoxycarbonyl)amino]isoindoline-1,3-dione; Boc-Protected Allyl Phthalimide; N-Allyl-N-Boc-phthalimide
EINECS	Contact for details

Quality Control

Our tert-Butyl Allyl(1,3-Dioxoisoindolin-2-Yl)Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GMP (Good Manufacturing Practice) environments and research requiring high-fidelity chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.