Description

3H-Oxazolo[3,4-A]Pyridin-3-One,1-Ethylhexahydro-6,7-Dihydroxy-,(1S,6S,7R,8As)-(9Ci) is a high-purity, stereochemically defined heterocyclic compound with significant potential in advanced organic synthesis. Its unique fused oxazolo-pyridinone structure and multiple chiral centers make it a valuable key intermediate for constructing complex molecular architectures. This compound is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to induce high enantioselectivity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for hit-to-lead optimization.
• Fine Chemical Production: Acts as a specialized intermediate for manufacturing high-value agrochemicals, flavors, or fragrances requiring specific stereochemistry.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Process Chemistry Development: Investigated for scalable synthetic routes in pilot plants and kilo-lab settings.

Basic Information

Product Name	3H-Oxazolo[3,4-A]Pyridin-3-One,1-Ethylhexahydro-6,7-Dihydroxy-,(1S,6S,7R,8As)-(9Ci)
CAS No.	287185-05-1
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	(1S,6S,7R,8aS)-1-Ethylhexahydro-6,7-dihydroxy-3H-oxazolo[3,4-a]pyridin-3-one; 1-Ethylhexahydro-6,7-dihydroxy-3H-oxazolo[3,4-a]pyridin-3-one, (1S,6S,7R,8aS)-; (1S,6S,7R,8aS)-1-Ethyl-6,7-dihydroxyoctahydro-3H-oxazolo[3,4-a]pyridin-3-one; 287185-05-1; (8aS)-1-Ethyl-6,7-dihydroxyhexahydro-3H-oxazolo[3,4-a]pyridin-3-one; UNII-8P4Q3J3Q0I; SCHEMBL218062; ZINC000253909991.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We provide comprehensive analytical data to support your research and regulatory filings. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are available for each lot. Our standard quality commitment aligns with the requirements for cGMP starting materials and ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.