Description

1,4-Oxazepin-7(2H)-One, Tetrahydro-4-(Trifluoroacetyl)- (9Ci) is a high-purity, specialized heterocyclic organic compound featuring a fused oxazepine ring system and a reactive trifluoroacetyl group. This unique structure makes it a critical building block (advanced intermediate) for the synthesis of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers developing new therapeutic agents, where its specific scaffold is integral to creating target compounds with desired biological activity.

Application

This compound serves as a versatile and high-value synthetic intermediate. Its primary applications include:

• Pharmaceutical Intermediate: Key building block in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or other targeted therapies.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and create novel chemical libraries for screening.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, fluorinated organic molecules for various high-value applications beyond pharma.
• Agrochemical Research: Potential intermediate in the development of new generation herbicides or pesticides utilizing fluorinated heterocycles.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1,4-Oxazepin-7(2H)-One, Tetrahydro-4-(Trifluoroacetyl)- (9Ci)
CAS No.	286432-58-4
Molecular Formula	C8H8F3NO3
Molecular Weight	223.15 g/mol
Synonyms	4-(Trifluoroacetyl)tetrahydro-1,4-oxazepin-7(2H)-one; Tetrahydro-4-(trifluoroacetyl)-1,4-oxazepin-7(2H)-one; 1,4-Oxazepin-7(2H)-one, tetrahydro-4-(trifluoroacetyl)-; 286432-58-4; 4-Trifluoroacetyltetrahydro-1,4-oxazepin-7-one; 7-Oxo-4-(trifluoroacetyl)hexahydro-1,4-oxazepine
EINECS	Contact for details

Quality Control

We supply 1,4-Oxazepin-7(2H)-One, Tetrahydro-4-(Trifluoroacetyl)- (9Ci) in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We adhere to a cGMP-compliant quality management system for manufacturing and control, ensuring traceability and reliability for critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, maintaining the material at 2-8°C under an inert atmosphere is recommended to preserve stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.