Description

4-[(6,7-Dimethoxy-4-Quinolyl)Oxy]-2-Chloroaniline is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of targeted therapeutic agents, offering researchers and manufacturers a reliable building block for drug discovery and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical producers engaged in creating novel small-molecule drugs, particularly in oncology and other specialized therapeutic areas.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, particularly kinase inhibitors.
• Oncology Research & Development: Used in the discovery and development of targeted cancer therapies due to its quinoline-based scaffold.
• Fine Chemical Manufacturing: Employed in the production of high-value, complex active pharmaceutical ingredients (APIs) for clinical trials and commercial supply.
• Biochemical Research: Acts as a tool compound or a starting material for creating specialized probes in biochemical and pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.

Basic Information

Product Name	4-[(6,7-Dimethoxy-4-Quinolyl)Oxy]-2-Chloroaniline
CAS No.	286371-44-6
Molecular Formula	C17H15ClN2O3
Molecular Weight	330.77 g/mol
Synonyms	2-Chloro-4-[(6,7-dimethoxy-4-quinolinyl)oxy]aniline; 2-Chloro-4-(6,7-dimethoxyquinolin-4-yloxy)aniline; 4-(2-Chloro-4-aminophenoxy)-6,7-dimethoxyquinoline; 286371-44-6; 4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2-chloro-benzenamine
EINECS	Contact for details

Quality Control

Our 4-[(6,7-Dimethoxy-4-Quinolyl)Oxy]-2-Chloroaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of our global clientele in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.