Description

Dichloroacetic Acid-2-13C is a stable isotope-labeled analog of dichloroacetic acid, where the carbon atom at the 2-position is enriched with the 13C isotope. This compound is essential as a high-purity internal standard and tracer in quantitative analytical research, particularly in mass spectrometry-based metabolomic and pharmacokinetic studies. It is primarily utilized by research institutions, pharmaceutical development labs, and analytical service providers requiring precise measurement and tracking of dichloroacetic acid and related metabolic pathways.

Application

• Internal Standard for Quantitative Analysis: Used in GC-MS and LC-MS methods for the accurate quantification of dichloroacetic acid in complex biological and environmental matrices.
• Metabolic Pathway Tracer: Enables the study of the metabolism and biochemical fate of dichloroacetic acid in in vitro and in vivo systems.
• Pharmaceutical Research: Supports drug metabolism and pharmacokinetics (DMPK) studies for compounds metabolized to or interacting with dichloroacetic acid.
• Environmental Analysis: Serves as a labeled standard for detecting and quantifying trace levels of dichloroacetic acid, a disinfection byproduct, in water samples.
• Biochemical Research: Investigates the role of dichloroacetic acid in cellular processes, including its effects on pyruvate dehydrogenase kinase.
• Certified Reference Material (CRM) Production: Acts a key component in formulating high-accuracy calibration standards and certified reference materials for analytical laboratories.

Basic Information

Item	Detail
Product Name	Dichloroacetic Acid-2-13C
CAS No.	286367-78-0
Molecular Formula	C13CHCl2COOH
Molecular Weight	129.93 g/mol (approx.)
Synonyms	2-13C-Dichloroacetic Acid; [2-13C]Dichloroacetic Acid; Dichloroacetic-2-13C Acid; DCA-2-13C; 13C-Labeled Dichloroacetic Acid; (13C)Dichloroacetic Acid; Dichloroacetic Acid (13C Labeled); Isotopic Labeled Dichloroacetic Acid
EINECS	Contact for details

Quality Control

Every batch of Dichloroacetic Acid-2-13C is manufactured and analyzed under strict quality protocols to ensure exceptional isotopic and chemical purity, critical for sensitive analytical applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (atom % 13C), chemical purity by HPLC, and identity confirmation by NMR and MS. Our quality system is designed to meet the rigorous standards required for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent; ensure containers are kept tightly sealed to exclude moisture and stored separately from bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (Atom % 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Isotopic Enrichment (Position 2)	≥ 99%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.