Description

3-Boc-Amino-3-(2'-Chlorophenyl)Propionic Acid CAS NO 284493-66-9 is a high-purity, protected amino acid derivative featuring a Boc (tert-butoxycarbonyl) protecting group and a 2-chlorophenyl substituent. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and other bioactive molecules.
• API Synthesis: Used in the research and production of Active Pharmaceutical Ingredients (APIs) targeting neurological and metabolic disorders.
• Agrochemical Research: Serves as a building block for developing novel herbicides and pesticides with specific chiral activity.
• Peptide Chemistry: Employed in solid-phase and solution-phase peptide synthesis where the Boc group provides orthogonal protection.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and receptor binding.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects in fine chemical and CDMO (Contract Development and Manufacturing Organization) settings.

Basic Information

Product Name	3-Boc-Amino-3-(2'-Chlorophenyl)Propionic Acid
CAS No.	284493-66-9
Molecular Formula	C14H18ClNO4
Molecular Weight	299.75 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-3-(2-chlorophenyl)propanoic acid; (R/S)-3-(Boc-amino)-3-(2-chlorophenyl)propionic acid; 3-(tert-Butoxycarbonylamino)-3-(2-chlorophenyl)propanoic acid; 3-(Boc-amino)-3-(o-chlorophenyl)propionic acid; Boc-3-amino-3-(2-chlorophenyl)propionic acid; N-Boc-3-amino-3-(2-chlorophenyl)propanoic acid; 2-Chlorophenylalanine Boc derivative; tert-Butyl 3-carboxy-3-(2-chlorophenyl)propylcarbamate
EINECS	Contact for details

Quality Control

Our 3-Boc-Amino-3-(2'-Chlorophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the Certificate of Analysis. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.