Description

3-n-Boc-3-(2-Fluorophenyl)Propionic Acid CAS NO 284493-56-7 is a high-purity, protected amino acid derivative featuring a Boc (tert-butoxycarbonyl) protecting group and a fluorinated aromatic side chain. This compound is a critical pharmaceutical intermediate used in the synthesis of complex active pharmaceutical ingredients (APIs), where its structure provides essential chemical functionality and stability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of peptide-based drugs and other complex organic molecules.
• API Development: Used in research and development for creating new active pharmaceutical ingredients, particularly those targeting neurological and oncological pathways.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Chemical Research: Employed in academic and industrial laboratories for medicinal chemistry and process chemistry research.
• Prodrug Synthesis: Utilized in the design and synthesis of prodrugs due to the cleavable Boc protecting group.
• Fluorinated Compound Libraries: Acts as a valuable component for generating libraries of fluorinated compounds in drug discovery programs.

Basic Information

Product Name	3-n-Boc-3-(2-Fluorophenyl)Propionic Acid
CAS No.	284493-56-7
Molecular Formula	C₁₄H₁₇FNO₄
Molecular Weight	282.29 g/mol
Synonyms	3-(tert-Butoxycarbonylamino)-3-(2-fluorophenyl)propanoic acid; 3-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-(2-fluorophenyl)propanoic acid; 3-(Boc-amino)-3-(2-fluorophenyl)propionic acid; Boc-2-fluoro-DL-phenylalanine-OH; 3-(N-Boc-amino)-3-(2-fluorophenyl)propanoic acid; 2-Fluorophenylalanine N-Boc derivative; N-(tert-Butoxycarbonyl)-2-fluoro-DL-phenylalanine
EINECS	Contact for details

Quality Control

Our 3-n-Boc-3-(2-Fluorophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with standards expected for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.