Description

3-n-Boc-3-(3-Nitrophenyl)Propionic Acid CAS NO 284492-22-4 is a high-purity, protected amino acid derivative featuring both a tert-butoxycarbonyl (Boc) protecting group and a nitrophenyl moiety. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research and development chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing peptidomimetics and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in protease inhibitor and CNS-active compound research.
• Peptidomimetic Synthesis: Serves as a protected amino acid building block for constructing non-peptide scaffolds that mimic peptide structure and function.
• Agrochemical Research: Used in the development of advanced herbicides and pesticides where specific chiral centers are required for biological activity.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in asymmetric synthesis and protecting group chemistry.
• Custom Synthesis: A starting material for the custom manufacturing of more complex, target-specific molecules for client projects.
• Chemical Biology Probes: Utilized in the creation of labeled or tagged molecules for studying biological pathways and enzyme mechanisms.

Basic Information

Product Name	3-n-Boc-3-(3-Nitrophenyl)Propionic Acid
CAS No.	284492-22-4
Molecular Formula	C14H17NO6
Molecular Weight	295.29 g/mol
Synonyms	3-(3-Nitrophenyl)-3-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic Acid; (R/S)-3-[(tert-Butoxycarbonyl)amino]-3-(3-nitrophenyl)propanoic Acid; 3-(Boc-amino)-3-(3-nitrophenyl)propionic Acid; 3-(3-Nitrophenyl)-3-[(tert-butoxycarbonyl)amino]propanoic Acid; 3-[(tert-Butoxycarbonyl)amino]-3-(3-nitrophenyl)propanoic Acid; Boc-3-(3-NO2-Phe)-OH; β-(3-Nitrophenyl)-β-[(tert-butoxycarbonyl)amino]propionic Acid
EINECS	Contact for details

Quality Control

Our 3-n-Boc-3-(3-Nitrophenyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.