Description

3-n-Fmoc-3-(2-Fluorophenyl)Propionic Acid CAS NO 284492-05-3 is a specialized, high-purity fluorinated building block designed for advanced organic synthesis. This compound is critical for the efficient and precise construction of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and bioactive compounds. It is an essential reagent for medicinal chemists and researchers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for peptide synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key fluorinated building block in the solid-phase and solution-phase synthesis of novel peptide-based drugs and therapeutic candidates.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities (NCEs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas where fluorination enhances metabolic stability and bioavailability.
• Peptide Synthesis: Serves as a protected amino acid derivative (Fmoc-protected) for the automated synthesis of custom peptides and peptidomimetics.
• Agrochemical Development: Employed in the research and synthesis of advanced, fluorinated agrochemicals such as herbicides and pesticides, where the fluorine atom can improve efficacy and environmental profile.
• Chemical Biology Probes: Utilized in the creation of labeled probes and tools for studying biological processes and protein interactions.
• Material Science: A potential monomer or precursor for synthesizing specialty polymers and advanced organic materials with tailored properties.

Basic Information

Product Name	3-n-Fmoc-3-(2-Fluorophenyl)Propionic Acid
CAS No.	284492-05-3
Molecular Formula	C24H19FNO4
Molecular Weight	404.41 g/mol
Synonyms	3-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(2-fluorophenyl)propanoic Acid; Fmoc-3-(2-Fluorophenyl)-β-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-fluorophenyl)-β-alanine; 3-(2-Fluorophenyl)-3-[(9H-fluoren-9-ylmethoxy)formamido]propanoic Acid; 3-(Fmoc-amino)-3-(2-fluorophenyl)propionic Acid; N-Fmoc-3-(2-fluorophenyl)-β-alanine; 2-Fluoro-N-Fmoc-phenylalanine derivative; β-Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-(2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 3-n-Fmoc-3-(2-Fluorophenyl)Propionic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and desiccated when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.