Description

.Beta.-D-Glucopyranoside, Methyl 2-Deoxy-2-1-(4,4-Dimethyl-2,6-Dioxocyclohexylidene)Ethylamino-1-Thio- is a sophisticated thioglycoside derivative, a key building block in synthetic carbohydrate chemistry. Its value lies in its role as a protected glycosyl donor, enabling the stereoselective construction of complex oligosaccharides and glycoconjugates. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for the development of novel therapeutics, vaccines, and diagnostic agents.

Application

• Glycoconjugate Synthesis: A critical precursor for the chemical and enzymatic synthesis of biologically active glycoconjugates, including glycoproteins and glycolipids.
• Oligosaccharide Assembly: Serves as a versatile glycosyl donor in automated and solution-phase oligosaccharide synthesis for drug discovery and basic research.
• Pharmaceutical Intermediates: Used in the research and development of carbohydrate-based drugs, such as antiviral agents, antibiotics, and anti-cancer therapeutics.
• Biochemical Probes: Employed in the creation of labeled sugars and probes for studying carbohydrate-protein interactions and metabolic pathways.
• Vaccine Development: Facilitates the synthesis of carbohydrate antigens for conjugate vaccine candidates against bacterial pathogens.
• Enzyme Substrate Synthesis: Used to prepare specific substrates for glycosidase and glycosyltransferase enzyme studies and inhibitor screening.

Basic Information

Item	Details
Product Name	.Beta.-D-Glucopyranoside, Methyl 2-Deoxy-2-1-(4,4-Dimethyl-2,6-Dioxocyclohexylidene)Ethylamino-1-Thio-
CAS No.	282526-14-1
Molecular Formula	C17H27NO6S
Molecular Weight	373.47 g/mol
Synonyms	Methyl 2-Deoxy-2-[(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]-1-thio-β-D-glucopyranoside; 1-Thio-β-D-glucopyranoside, methyl 2-deoxy-2-[(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]-; Methyl 1-thio-β-D-glucopyranoside derivative; Protected thioglucoside donor; DIMEDONE-protected glucosamine thioglycoside; Glycosyl donor building block; Carbohydrate synthesis intermediate
EINECS	Contact for details

Quality Control

Our .Beta.-D-Glucopyranoside, Methyl 2-Deoxy-2-1-(4,4-Dimethyl-2,6-Dioxocyclohexylidene)Ethylamino-1-Thio- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and rigorous internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.