Description

6,8-Dioxabicyclo[3.2.1]Octane,2-Fluoro-1,5-Dimethyl-,(1S,2S,5S)-(9Ci) is a high-purity, stereochemically defined fluorinated bicyclic ether building block. This compound matters for its unique structural features, combining a rigid bicyclic scaffold with fluorine substitution, which is critical for modulating the physicochemical and metabolic properties of advanced molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where precise stereochemistry and fluorine incorporation are required for target activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in creating advanced, fluorinated active ingredients for crop protection products with enhanced efficacy and environmental profile.
• Material Science Research: Serves as a specialized monomer or cross-linking agent in the development of novel fluorinated polymers with specific thermal or chemical resistance.
• Asymmetric Catalysis: Potential use as a chiral ligand or auxiliary in stereoselective synthetic transformations.
• Chemical Biology Probes: Employed in the design of molecular probes to study enzyme mechanisms or biological pathways due to its fluorine label and defined geometry.

Basic Information

Product Name	6,8-Dioxabicyclo[3.2.1]Octane,2-Fluoro-1,5-Dimethyl-,(1S,2S,5S)-(9Ci)
CAS No.	281193-52-0
Molecular Formula	C8H13FO2
Molecular Weight	160.18 g/mol
Synonyms	(1S,2S,5S)-2-Fluoro-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane; 2-Fluoro-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane, (1S,2S,5S)-; (1S,2S,5S)-2-Fluoro-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane (9CI); Fluorinated Bicyclic Acetal; (1S,2S,5S)-exo-2-Fluoro-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane
EINECS	Contact for details

Quality Control

Our 6,8-Dioxabicyclo[3.2.1]Octane,2-Fluoro-1,5-Dimethyl-,(1S,2S,5S)-(9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with customer specifications and research-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.