Description

3-Cyano-4-Fluorophenylhydrazine Hcl CAS NO 280120-91-4 is a high-purity, functionalized phenylhydrazine derivative that serves as a critical pharmaceutical intermediate and organic synthesis building block. Its molecular structure, featuring both cyano and fluoro substituents, makes it a versatile precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of novel therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the bioactivity of the fluorinated phenylhydrazine core.
• Heterocyclic Chemistry: Essential precursor for constructing pyrazole, indazole, and other nitrogen-containing heterocycles important in medicinal chemistry.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: A valuable reagent for method development and exploring new reaction pathways in academic and industrial laboratories.
• Dye and Pigment Industry: Intermediate in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	3-Cyano-4-Fluorophenylhydrazine Hydrochloride
CAS No.	280120-91-4
Molecular Formula	C7H7FN3·HCl
Molecular Weight	187.60 g/mol (Free base) / 224.06 g/mol (HCl salt)
Synonyms	(4-Fluoro-3-cyanophenyl)hydrazine hydrochloride; 1-(4-Fluoro-3-cyanophenyl)hydrazine hydrochloride; 3-Cyano-4-fluorophenylhydrazine hydrochloride; 4-Fluoro-3-cyanophenylhydrazine HCl; Hydrazine, (4-fluoro-3-cyanophenyl)-, hydrochloride; 280120-91-4; 3-Fluoro-4-cyanophenylhydrazine hydrochloride (isomer)
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-Fluorophenylhydrazine HCl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.