Description

4-(2H-Pyrazol-3-Yl)-Piperidine CAS NO 278798-08-6 is a high-value, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound is a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and process development for central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical scaffold in the synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used as a versatile building block for constructing focused libraries and exploring structure-activity relationships (SAR).
• Ligand Synthesis: Employed in the development of novel ligands for biological targets, including kinases and GPCRs.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and pesticides.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and protein function.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	4-(2H-Pyrazol-3-Yl)-Piperidine
CAS No.	278798-08-6
Molecular Formula	C8H13N3
Molecular Weight	151.21 g/mol
Synonyms	4-(1H-Pyrazol-5-yl)piperidine; 4-(1H-Pyrazol-5-yl)piperidine; 4-(2H-Pyrazol-3-yl)piperidine; 4-(1H-Pyrazol-5-yl)piperidine; Piperidine, 4-(1H-pyrazol-5-yl)-; 4-(1H-Pyrazol-5-yl)piperidine; 4-Pyrazol-3-yl-piperidine
EINECS	Contact for details

Quality Control

Our 4-(2H-Pyrazol-3-Yl)-Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.