Description

2-[4-(Trifluoromethyl)Anilino]-4H-3,1-Benzoxazin-4-One is a specialized heterocyclic organic compound featuring a benzoxazinone core substituted with a trifluoromethyl anilino group. This structure makes it a valuable high-purity chemical intermediate for advanced synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating novel molecules with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, or insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology Probe Development: Utilized in academic and industrial R&D to create molecular probes for studying enzyme function or biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-[4-(Trifluoromethyl)Anilino]-4H-3,1-Benzoxazin-4-One
CAS No.	278609-56-6
Molecular Formula	C15H9F3N2O2
Molecular Weight	306.24 g/mol
Synonyms	2-[(4-Trifluoromethyl)anilino]-4H-3,1-benzoxazin-4-one; 2-[(4-Trifluoromethylphenyl)amino]-4H-3,1-benzoxazin-4-one; 4H-3,1-Benzoxazin-4-one, 2-[[4-(trifluoromethyl)phenyl]amino]-; 2-(4-Trifluoromethyl-anilino)-4H-3,1-benzoxazin-4-on; 278609-56-6; Benzoxazinone derivative with trifluoromethyl anilino group
EINECS	Contact for details

Quality Control

Our 2-[4-(Trifluoromethyl)Anilino]-4H-3,1-Benzoxazin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical and advanced agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.