Description

2-Chloro-n-Methyl-n-1,2,3,4-Tetrahydronaphthalen-1-Ylacetamide is a specialized organic compound featuring a tetrahydronaphthalene (tetralin) backbone, a key structural motif in medicinal chemistry. This molecule serves as a critical synthetic intermediate for the development of novel pharmacologically active agents, particularly in central nervous system (CNS) and cardiovascular research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex, high-value target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the biological activity of tetralin-derived compounds.
• Fine Chemical Synthesis: Serves as a precursor for the production of more complex chiral molecules and active pharmaceutical ingredients (APIs).
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic chemistry and pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	2-Chloro-n-Methyl-n-1,2,3,4-Tetrahydronaphthalen-1-Ylacetamide
CAS No.	276886-84-1
Molecular Formula	C₁₄H₁₆ClNO
Molecular Weight	249.74 g/mol
Synonyms	2-Chloro-N-methyl-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide; N-Methyl-2-chloro-N-(1,2,3,4-tetrahydro-1-naphthyl)acetamide; 1-[(2-Chloroacetyl)(methyl)amino]-1,2,3,4-tetrahydronaphthalene; 2-Chloro-N-methyl-N-(1,2,3,4-tetrahydro-1-naphthalenyl)acetamide; Tetralin-1-yl Chloroacetamide Derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-Methyl-n-1,2,3,4-Tetrahydronaphthalen-1-Ylacetamide is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for materials intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.