Description

Sodium Difluoromethanesulfinate is a versatile organosulfur compound that serves as a key reagent for introducing the difluoromethylsulfinyl group. Its value lies in its ability to act as a nucleophilic difluoromethylating agent, enabling the synthesis of complex fluorinated molecules which are crucial in modern material and pharmaceutical science. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise fluorination capabilities to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of protease inhibitors and other biologically active molecules containing the difluoromethyl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where fluorination enhances metabolic stability and bioactivity.
• Material Science: Employed in the creation of fluorinated polymers, surfactants, and liquid crystals with unique thermal, chemical, and surface properties.
• Organic Synthesis Reagent: Functions as a nucleophilic difluoromethylsulfinylating agent in various C–C and C–heteroatom bond-forming reactions under mild conditions.
• Radiochemistry & Tracer Development: Potential use in the synthesis of fluorinated compounds for Positron Emission Tomography (PET) imaging agents.
• Cross-Coupling Reactions: Serves as a coupling partner in palladium-catalyzed reactions to construct complex, fluorinated molecular architectures.

Basic Information

Item	Detail
Product Name	Sodium Difluoromethanesulfinate
CAS No.	275818-95-6
Molecular Formula	CHF2SO2Na
Molecular Weight	144.06 g/mol
Synonyms	Sodium Difluoromethanesulfinate; Difluoromethanesulfinic Acid Sodium Salt; Sodium Difluoromethylsulfinate; DFMS-Na; Sodium (Difluoromethyl)sulfinate; Difluoromethylsulfinic Acid Sodium Salt; Sodium 1,1-Difluoromethanesulfinate
EINECS	Contact for details

Quality Control

Our Sodium Difluoromethanesulfinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee supply reliability and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.