Description

3H-Pyrazol-3-One, 1,2-Dihydro-4-[[8-(Methylsulfonyl)-5-Quinolinyl]Carbonyl]- is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Reagent: Serves as a reference standard or inhibitor in enzymatic and receptor-binding assays.
• Fine Chemical Synthesis: Intermediate for the production of complex, high-value specialty chemicals with quinoline and pyrazolone motifs.
• Academic Research: Utilized in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry projects.

Basic Information

Product Name	3H-Pyrazol-3-One, 1,2-Dihydro-4-[[8-(Methylsulfonyl)-5-Quinolinyl]Carbonyl]-
CAS No.	274681-25-3
Molecular Formula	C14H11N3O4S
Molecular Weight	317.32 g/mol
Synonyms	1,2-Dihydro-4-[(8-methylsulfonyl-5-quinolinyl)carbonyl]-3H-pyrazol-3-one; 4-[(8-Methanesulfonylquinolin-5-yl)carbonyl]-1,2-dihydro-3H-pyrazol-3-one; 4-(8-Methylsulfonylquinoline-5-carbonyl)-1,2-dihydropyrazol-3-one; 274681-25-3; 8-(Methylsulfonyl)-5-quinolinecarboxylic acid, 1,2-dihydro-3-oxo-3H-pyrazol-4-yl ester; Quinoline-5-carbonyl pyrazolone derivative
EINECS	Contact for details

Quality Control

Our production of 3H-Pyrazol-3-One, 1,2-Dihydro-4-[[8-(Methylsulfonyl)-5-Quinolinyl]Carbonyl]- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.