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3-Aminopropyl B-D-Lactose CAS NO 273937-97-6


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CAS No.:273937-97-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Aminopropyl B-D-Lactose is a specialized bifunctional chemical building block that combines a reactive primary amine group with a lactose-derived carbohydrate moiety. This unique structure makes it a critical intermediate for the synthesis of targeted glycoconjugates and bioconjugates, enabling precise molecular engineering. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors who require high-purity linkers for advanced drug delivery systems, vaccine development, and affinity chromatography media.

Application

  • Pharmaceutical Conjugation: Key intermediate for synthesizing antibody-drug conjugates (ADCs) and other targeted therapeutics.
  • Glycobiology Research: Used to create neoglycoconjugates for studying carbohydrate-protein interactions and cell signaling.
  • Diagnostic Reagent Synthesis: Serves as a linker for attaching enzymes, fluorophores, or other labels to antibodies and proteins in assay development.
  • Affinity Chromatography Ligand: Functional group for immobilizing biomolecules onto solid supports for purification processes.
  • Biomaterial Modification: Employed to introduce hydrophilic and bioactive carbohydrate motifs onto polymer surfaces or nanoparticles.
  • Vaccine Adjuvant Development: Potential use in constructing novel carbohydrate-based adjuvants to modulate immune responses.

Basic Information

Product Name 3-Aminopropyl B-D-Lactose
CAS No. 273937-97-6
Molecular Formula C15H29NO11
Molecular Weight 399.39 g/mol
Synonyms 3-Aminopropyl β-D-Lactoside; β-D-Lactosylpropylamine; Lactosylpropylamine; N-(3-Aminopropyl)-β-D-lactoside; 1-O-[2-(Aminomethyl)ethyl]-β-D-lactopyranoside; 3-AP-Lactose; Lactose-3-aminopropyl conjugate; Glycosylaminopropyl linker
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Quality Control

Our 3-Aminopropyl B-D-Lactose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR / NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Heavy Metals ≤ 20 ppm
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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