Description

Methyl-D-Erythritol Phosphate CAS NO 270928-69-3 is a key phosphorylated intermediate in the non-mevalonate (MEP/DOXP) pathway for isoprenoid biosynthesis. This compound is of significant value for biochemical research and the development of novel antimicrobial agents, as it is a precursor to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). It is primarily needed by researchers in pharmaceutical development, agrochemical discovery, and academic institutions studying metabolic pathways and enzyme inhibition.

Application

• Biochemical Research: Critical substrate for studying the enzymes of the MEP pathway, such as IspC (DXP reductoisomerase).
• Pharmaceutical Development: Serves as a target molecule for the design of novel antibiotics, antimalarials, and herbicides that disrupt essential isoprenoid synthesis in pathogens and plants.
• Enzyme Inhibition Studies: Used to evaluate and characterize inhibitors of DXP reductoisomerase, a validated target for infectious disease treatment.
• Metabolic Pathway Analysis: Employed in tracer studies and metabolic flux analysis to understand isoprenoid production in engineered microbial systems.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical and biotech laboratories.
• Agrochemical Research: Investigated for the development of next-generation plant growth regulators and herbicides that target weed-specific metabolic pathways.

Basic Information

Product Name	Methyl-D-Erythritol Phosphate
CAS No.	270928-69-3
Molecular Formula	C5H13O7P
Molecular Weight	216.12 g/mol
Synonyms	MEP; 2-C-Methyl-D-erythritol 4-phosphate; 4-(Hydroxyphosphinyloxy)-2-C-methyl-D-erythritol; (2R,3S)-1-(Dihydroxyphosphoryloxy)-3-methylbutane-2,3,4-triol; 2-C-Methyl-D-erythritol-4-phosphate; CDP-ME; MEP (biochemical intermediate); 1-Deoxy-D-xylulose-5-phosphate pathway intermediate
EINECS	Contact for details

Quality Control

Our Methyl-D-Erythritol Phosphate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic nature, containers should be allowed to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.