Description

(5R,6R)-1-Benzyl-5-Hydroxy-6-(Methylamino)-5,6-Dihydro-4H-Imidazo[4,5,1-Ij]Chinoline-2(1H)-On is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research. It is essential for pharmaceutical R&D laboratories and manufacturers engaged in the development of proprietary active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates targeting specific biological pathways.
• Neurological Research: Used in the development of compounds for studying and treating neurological disorders and CNS conditions.
• Oncological Drug Discovery: Serves as a precursor in the creation of novel small-molecule inhibitors for cancer therapy research.
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale manufacturing for new chemical entities (NCEs).
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for medicinal chemistry programs.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control.

Basic Information

Product Name	(5R,6R)-1-Benzyl-5-Hydroxy-6-(Methylamino)-5,6-Dihydro-4H-Imidazo[4,5,1-Ij]Chinoline-2(1H)-On
CAS No.	269731-84-2
Molecular Formula	C19H20N4O2
Molecular Weight	336.39 g/mol
Synonyms	(5R,6R)-1-Benzyl-5-hydroxy-6-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one; 1-Benzyl-5-hydroxy-6-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (5R,6R)-; (5R,6R)-1-Benzyl-5-hydroxy-6-methylamino-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one; 269731-84-2; (5R,6R)-1-Benzyl-5-hydroxy-6-(methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinoline-2(1H)-one
EINECS	Contact for details

Quality Control

Our (5R,6R)-1-Benzyl-5-Hydroxy-6-(Methylamino)-5,6-Dihydro-4H-Imidazo[4,5,1-Ij]Chinoline-2(1H)-On is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP (current Good Manufacturing Practice) applications where specified. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider handling under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.