Description

Boc-(R)-3-Amino-4-(2-Thienyl)-Butyric Acid is a high-purity, non-natural amino acid derivative featuring a thienyl side chain and a tert-butoxycarbonyl (Boc) protecting group. This compound is a critical chiral building block for the synthesis of complex pharmaceutical intermediates and bioactive peptides. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of protease inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Peptide Synthesis: Serves as a protected amino acid residue in solid-phase and solution-phase peptide synthesis for creating novel peptide sequences.
• Protease Inhibitor Development: Used in the design and construction of potential inhibitors for various proteolytic enzymes due to its specific stereochemistry and functional groups.
• Chemical Biology Research: Employed as a tool compound or building block in studying enzyme-substrate interactions and signal transduction pathways.
• Asymmetric Synthesis: Acts as a starting material or intermediate for the asymmetric synthesis of more complex chiral molecules in medicinal chemistry.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Boc-(R)-3-Amino-4-(2-Thienyl)-Butyric Acid
CAS No.	269726-89-8
Molecular Formula	C₁₃H₁₉NO₄S
Molecular Weight	285.36 g/mol
Synonyms	(R)-3-[(tert-Butoxycarbonyl)amino]-4-(thiophen-2-yl)butanoic acid; (R)-3-(Boc-amino)-4-(2-thienyl)butyric acid; Boc-D-β-homo-2-thienylalanine; Boc-(R)-3-Amino-4-(2-thienyl)butanoic acid; N-Boc-3-amino-4-(2-thienyl)butyric acid; (R)-N-Boc-3-Amino-4-(2-thienyl)butyric Acid; 2-Thiophenebutanoic acid, β-amino-, N-Boc-, (βR)-; BOC-(R)-3-AMINO-4-(2-THIENYL)BUTYRIC ACID
EINECS	Contact for details

Quality Control

Our Boc-(R)-3-Amino-4-(2-Thienyl)-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and pharmaceutical-grade standards. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.