Description

(R)-3-Amino-4-(3-Cyanophenyl)Butanoic Acid Hydrochloride CAS NO 269726-82-1 is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and advanced fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and specialty chemical industries for developing novel therapeutics and high-value chemical products.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of potential drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• Peptidomimetic Research: Serves as a constrained γ-amino acid analog for constructing novel peptide-like structures in medicinal chemistry.
• Asymmetric Synthesis: Used as a starting material or reagent in catalytic asymmetric reactions to introduce chirality into complex molecular architectures.
• Chemical Biology Probes: Employed in the development of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic & Industrial R&D: Utilized in discovery chemistry for screening libraries and investigating structure-activity relationships (SAR).

Basic Information

Item	Detail
Product Name	(R)-3-Amino-4-(3-Cyanophenyl)Butanoic Acid Hydrochloride
CAS No.	269726-82-1
Molecular Formula	C11H13N3O2 • HCl
Molecular Weight	255.70 g/mol
Synonyms	(R)-3-Amino-4-(3-cyanophenyl)butanoic acid hydrochloride; (3R)-3-Amino-4-(3-cyanophenyl)butanoic acid hydrochloride; (R)-3-Amino-4-(3-cyanophenyl)butyric acid HCl; γ-Amino-β-(3-cyanophenyl)-(R)-butanoic acid hydrochloride; (R)-AABA(3-CN)Ph hydrochloride; (R)-3-Amino-4-(m-cyanophenyl)butanoic acid hydrochloride; (R)-H-β-homo-Phe(3-CN)-OH • HCl
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-4-(3-Cyanophenyl)Butanoic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.