Description

(R)-3-Amino-4-(4-Pyridyl)-Butyric Acid-2Hcl CAS NO 269396-67-0 is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its role as a key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, where its defined stereochemistry is critical for biological activity. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel therapeutics and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapies.
• API Synthesis: Serves as a key building block in multi-step synthetic routes for Active Pharmaceutical Ingredients (APIs) requiring precise stereochemical control.
• Biochemical Research: Used in academic and industrial R&D for studying enzyme inhibitors, receptor ligands, and other biologically active molecules.
• Agrochemical Development: Employed as an intermediate in the synthesis of advanced, chiral pesticides and herbicides.
• Peptidomimetics & Conjugate Chemistry: The amino and carboxylic acid functional groups make it suitable for constructing peptide analogs and bioconjugates.
• Catalyst & Ligand Preparation: Utilized in the development of chiral catalysts and ligands for asymmetric synthesis.

Basic Information

Product Name	(R)-3-Amino-4-(4-Pyridyl)-Butyric Acid-2Hcl
CAS No.	269396-67-0
Molecular Formula	C9H14N2O2 • 2HCl
Molecular Weight	279.14 g/mol
Synonyms	(R)-3-Amino-4-(4-pyridyl)butanoic acid dihydrochloride; (R)-3-Amino-4-(pyridin-4-yl)butyric acid hydrochloride; (3R)-3-Amino-4-(4-pyridinyl)butanoic acid dihydrochloride; (R)-4-Pyridylhomobeta-alanine-2HCl; (R)-Homo-β-(4-pyridyl)-alanine dihydrochloride; (R)-3-Amino-4-(4-pyridyl)butyric acid hydrochloride salt
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-4-(4-Pyridyl)-Butyric Acid-2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with stringent specifications for pharmaceutical-grade intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.