Description

Boc-(R)-3-Amino-4-(3-Pyridyl)-Butyric Acid is a high-purity, non-natural amino acid derivative featuring a Boc-protected amine group and a pyridyl side chain. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Peptidomimetic Synthesis: Used to incorporate a constrained, heterocyclic amino acid analog into peptide chains to enhance metabolic stability and binding affinity.
• Chemical Biology Research: Serves as a building block for creating molecular probes and labeled compounds to study biological pathways.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis or metal-chelating agents.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	Boc-(R)-3-Amino-4-(3-Pyridyl)-Butyric Acid
CAS No.	269396-65-8
Molecular Formula	C14H20N2O4
Molecular Weight	280.32 g/mol
Synonyms	(R)-3-[(tert-Butoxycarbonyl)amino]-4-(3-pyridinyl)butanoic Acid; (R)-3-(Boc-Amino)-4-(3-pyridyl)butyric Acid; Boc-D-3-Amino-4-(3-pyridyl)butyric Acid; (R)-Boc-3-Amino-4-(3-pyridyl)butanoic Acid; tert-Butyl (R)-(1-carboxy-3-(pyridin-3-yl)propyl)carbamate; 269396-65-8; Boc-3-Amino-4-(3-Pyridyl)-Butyric Acid (R-isomer)
EINECS	Contact for details

Quality Control

Our Boc-(R)-3-Amino-4-(3-Pyridyl)-Butyric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.