Description

Ethanone, 1-[(1R,2R,4S,5S)-3-Oxatricyclo[3.2.1.02,4]Oct-6-Yl]-, Rel- (9Ci) is a high-purity, stereochemically defined chiral building block featuring a complex, rigid oxatricyclic scaffold. This compound is of significant value for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where precise three-dimensional structure is critical for biological activity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation enhances efficacy and reduces environmental impact.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical and Flavor/Fragrance Intermediate: Employed in the synthesis of complex, high-value specialty chemicals and aroma molecules.
• Academic and Industrial Research: A valuable tool compound for methodological studies in organic chemistry, including cycloaddition reactions and scaffold diversification.
• Material Science Precursor: Potential use in the synthesis of monomers for advanced polymers with specific stereoregular properties.

Basic Information

Product Name	Ethanone, 1-[(1R,2R,4S,5S)-3-Oxatricyclo[3.2.1.02,4]Oct-6-Yl]-, Rel- (9Ci)
CAS No.	267003-43-0
Molecular Formula	C10H12O2
Molecular Weight	164.20 g/mol
Synonyms	rel-(1R,2R,4S,5S)-6-Acetyl-3-oxatricyclo[3.2.1.02,4]octane; (1R,2R,4S,5S)-6-Acetyl-3-oxatricyclo[3.2.1.02,4]octane (rel); 3-Oxatricyclo[3.2.1.02,4]octan-6-yl methyl ketone; 1-(3-Oxatricyclo[3.2.1.02,4]oct-6-yl)ethanone; Chiral Oxatricyclic Ketone; Acetylated Oxanorbornane Derivative
EINECS	Contact for details

Quality Control

Every batch of Ethanone, 1-[(1R,2R,4S,5S)-3-Oxatricyclo[3.2.1.02,4]Oct-6-Yl]-, Rel- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and enantiomeric excess meet your specific research or production requirements. A detailed Certificate of Analysis (COA) including chiral purity (HPLC), assay, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.