Description

2-Deoxy-D-[Ul-13C5]Erythro-Pentose is a stable isotope-labeled analog of 2-deoxy-D-ribose, a fundamental sugar moiety in DNA. This compound is specifically enriched with carbon-13 at all five carbon positions, making it an essential tool for advanced metabolic and biochemical research. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and diagnostic developers for applications in mass spectrometry, NMR spectroscopy, and tracer studies.

Application

• Metabolic Flux Analysis (MFA): Used as a carbon-13 labeled tracer to study the pentose phosphate pathway and nucleotide biosynthesis in cell cultures and biological systems.
• Biomarker Discovery & Proteomics: Serves as a precursor for synthesizing isotopically labeled nucleosides or nucleotides for mass spectrometry-based quantification in proteomic and metabolomic studies.
• Pharmaceutical Drug Development: Employed in the research and development of antiviral and anticancer agents that target nucleotide metabolism pathways.
• NMR Spectroscopy Standards: Acts as an internal standard for nuclear magnetic resonance (NMR) spectroscopy due to its uniform carbon-13 labeling, enabling precise structural and kinetic analysis.
• Diagnostic Assay Development: Used in the formulation of internal standards for LC-MS/MS assays to ensure accurate quantification of metabolites in clinical diagnostics.

Basic Information

Product Name	2-Deoxy-D-[Ul-13C5]Erythro-Pentose
CAS No.	266998-43-0
Molecular Formula	¹³C₅H₁₀O₄
Molecular Weight	~155.06 g/mol (based on ¹³C)
Synonyms	2-Deoxy-D-ribose-¹³C₅; [U-¹³C₅]-2-Deoxy-D-erythro-pentose; 2-Deoxy-D-[U-¹³C₅]ribose; Isotopically labeled 2-deoxyribose; 2-Deoxy-D-arabinose-¹³C₅; D-2-Deoxyribose (U-¹³C₅); 2-Desoxy-D-ribose-¹³C₅
EINECS	Contact for details

Quality Control

Every batch of our 2-Deoxy-D-[Ul-13C5]Erythro-Pentose is produced and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity to meet the exacting standards of research and development. Comprehensive Certificates of Analysis (COA) are provided, detailing parameters such as isotopic enrichment, chemical purity by HPLC, and specific optical rotation. Our quality commitment ensures reliable and reproducible performance in your most sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % ¹³C
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.