Description

5-Bromo-4-Chloroindol-3-Yl-5-Acetamido-3,5-Dideoxy-α-D-Glycero-D-Galacto 2-Nonulopyranosidonic Acid Ammonium is a sophisticated, high-purity biochemical intermediate, specifically a sialic acid derivative with a halogenated indole moiety. This compound is critical for advanced research and development in the life sciences, offering a precise building block for synthesizing complex glycoconjugates and probes. It is primarily utilized by pharmaceutical R&D teams, diagnostic developers, and academic researchers focused on glycobiology, neuraminidase studies, and the development of novel therapeutic agents and diagnostic tools.

Application

• Glycobiology Research: A key precursor for the synthesis of complex oligosaccharides, glycoproteins, and gangliosides to study cell-cell recognition, signaling, and immune response mechanisms.
• Enzyme Substrate & Inhibitor Development: Used in the design and synthesis of specific substrates or inhibitors for sialidases (neuraminidases) and sialyltransferases.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development stages of novel antiviral, antibacterial, or anticancer therapeutics targeting glycan-mediated processes.
• Diagnostic Reagent Synthesis: Employed in creating labeled probes and reagents for diagnostic assays, including fluorescence-based detection and imaging of sialic acid expression on cell surfaces.
• Bioconjugation & Probe Chemistry: The reactive indole and acetamido groups facilitate site-specific bioconjugation for creating antibody-drug conjugates (ADCs) or fluorescent molecular probes.
• Academic & Institutional Research: Supports fundamental studies in chemical biology, medicinal chemistry, and the structural analysis of carbohydrate-protein interactions.

Basic Information

Product Name	5-Bromo-4-Chloroindol-3-Yl-5-Acetamido-3,5-Dideoxy-α-D-Glycero-D-Galacto 2-Nonulopyranosidonic Acid Ammonium
CAS No.	265979-52-0
Molecular Formula	C₂₀H₂₇BrClN₃O₁₀ • xNH₃ (Contact for exact ammonium salt stoichiometry)
Molecular Weight	Approx. 584.81 g/mol (Free acid). Contact for details on ammonium salt form.
Synonyms	5-Bromo-4-chloro-3-indolyl-α-D-N-acetylneuraminic acid ammonium salt; 5-Bromo-4-chloro-3-indolyl-α-Neu5Ac ammonium salt; BCIP-α-Neu5Ac-NH₄; 5-Bromo-4-chloro-1H-indol-3-yl 5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-non-2-ulopyranosidonic acid ammonium salt; α-Sialyl-(5-Bromo-4-chloroindol-3-yl) ammonium salt; Chromogenic sialic acid substrate ammonium salt; CAS 265979-52-0
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Chloroindol-3-Yl-5-Acetamido-3,5-Dideoxy-α-D-Glycero-D-Galacto 2-Nonulopyranosidonic Acid Ammonium is manufactured and tested under a strict quality management system. We ensure compliance with rigorous internal specifications suitable for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity (Enzymatic)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.