Description

Dde-L-Lys(Alloc)-Oh Dcha is a specialized, high-purity protected amino acid derivative, widely recognized as a critical building block in solid-phase peptide synthesis (SPPS). This compound matters because it provides orthogonal protection for lysine side chains, enabling the precise, sequential construction of complex peptides and bioconjugates. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require reliable, high-quality intermediates for developing novel therapeutic peptides, diagnostic tools, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key protected lysine derivative for the controlled assembly of peptide chains.
• Orthogonal Protection Strategy: Enables selective deprotection of specific functional groups during multi-step synthetic sequences.
• Therapeutic Peptide Development: Used in the research and production of peptide-based pharmaceuticals, including hormones, antibiotics, and targeted cancer therapies.
• Bioconjugation and Labeling: Serves as a precursor for attaching peptides to other molecules, such as dyes, polymers, or drug carriers.
• Chemical Biology Research: A vital tool for studying protein-protein interactions and enzyme mechanisms.
• Antibody-Drug Conjugate (ADC) Synthesis: Used in the construction of linker-payload systems for targeted drug delivery.

Basic Information

Product Name	Dde-L-Lys(Alloc)-Oh Dcha
CAS No.	264230-73-1
Molecular Formula	C₂₀H₂₅N₃O₆ • C₁₄H₂₆N
Molecular Weight	~ 571.7 g/mol (Free acid)
Synonyms	Nε-(1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl)-Nα-(allyloxycarbonyl)-L-lysine Dicyclohexylamine Salt; Fmoc-Lys(Dde)-OH DCHA Salt (related); Nα-Alloc-Nε-Dde-L-lysine DCHA Salt; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl)amino)hexanoic acid Dicyclohexylamine Salt; Dde-Lys(Alloc)-OH•DCHA; Protected Lysine DCHA Salt; Orthogonally Protected Lysine Derivative; Peptide Synthesis Building Block.
EINECS	Contact for details

Quality Control

Our Dde-L-Lys(Alloc)-Oh Dcha is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.