Description

2-[(7-Methoxy-4-Methyl-2-Quinazolinyl)Amino]-4-Quinazolinol is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. This compound matters for its critical role as a key building block in the synthesis of novel, targeted therapeutic agents, particularly in oncology research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to develop and scale up production of innovative drug candidates.

Application

• Pharmaceutical Intermediate: Primary use as a sophisticated building block for synthesizing novel small-molecule drug candidates, especially kinase inhibitors.
• Oncology Research: Serves as a core scaffold in the development of targeted cancer therapies due to the quinazoline moiety's affinity for specific enzyme active sites.
• Biochemical Tool Compound: Used in academic and industrial research to study enzyme inhibition mechanisms and structure-activity relationships (SAR).
• Preclinical Development: Essential for producing batches of active pharmaceutical ingredients (APIs) for in-vitro and in-vivo testing during drug discovery phases.
• Process Chemistry: Employed in route scouting and optimization studies to develop efficient, scalable synthetic pathways for complex molecules.

Basic Information

Item	Detail
Product Name	2-[(7-Methoxy-4-Methyl-2-Quinazolinyl)Amino]-4-Quinazolinol
CAS No.	263747-01-9
Molecular Formula	C₁₈H₁₅N₅O₂
Molecular Weight	333.34 g/mol
Synonyms	4-Quinazolinol, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-; 2-((7-Methoxy-4-methylquinazolin-2-yl)amino)quinazolin-4-ol; 2-[(7-Methoxy-4-methylquinazolin-2-yl)amino]quinazolin-4-ol; 2-[(7-Methoxy-4-methyl-2-quinazolinyl)amino]-4(3H)-quinazolinone; CAS 263747-01-9
EINECS	Contact for details

Quality Control

Our 2-[(7-Methoxy-4-Methyl-2-Quinazolinyl)Amino]-4-Quinazolinol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.